PermaLink™ from Glythera

By: Glythera  08/01/2015
Keywords: drug development, Biotechnology Industry

Glythera’s PermaLink™ technology is a controlled, stable conjugation platform composed of a portfolio of linker designs. PermaLink™ can be employed for the selective and stable functionalization and conjugation of various cargos to proteins and peptides. Due to its increased stability and selectivity, PermaLink™ offers significant benefits in the development of next generation biologics: - Antibody Drug Conjugates - Conjugate vaccines - PEGylation PermaLink™ offers a number of other benefits including: - Comparative model system - Controlled Drug to Antibody Ratio (DAR) - Improved linker stability compared to maleimide based technologies - Comparable in vitro activity - Low immunogenic potential

Keywords: Biotechnology Industry, drug development

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PermaCarb™ from Glythera thumbnail


PermaCarb™ is an enabling discovery platform which uses stable glycan analogues to improve product performance and biobetter development. PermaCarb™ has been broad application in drug development.